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Showing posts from February, 2017

Position to work on tractability in Open Targets

There is currently an opening for a Protein Computational Scientist to work on methods to assess and quantify the tractability (druggability) of potential new targets for drug discovery. This is a two year position funded by the Open Targets initiative. The appointee will work with scientists from the Open Targets partners to assess, validate and develop methods for quantifying target tractability with the ultimate goal of incorporating such methodologies into the target validation platform (https://www.targetvalidation.org/). The initial focus will be on “small molecule” tractability but we are also interested in other modalities in due course (e.g. antibody therapies). Many of the current methods to assess small molecule tractability are based on the use of 3D protein structures, but such information is only available for a subset of potential targets; a key component of the project is to determine robust methods and pipelines that can be applied to novel targets where there i

ChEMBL Webinars

We will be running a new series of webinars over the next few months. These will cover a range of topics including basic introductions to the Chemogenomics resources (ChEMBL, SureChEMBL, UniChem) as well as more detailed topics, a schema walkthrough and ChEMBL web services. The first webinar will be a basic introduction to ChEMBL and will be on 22nd February at 2pm GMT (3pm CET, 9am EST). If you would like to attend the webinar, please email to register . Please note, spaces are limited so please let us know as soon as possible if you register but are then unable to attend. We will post further details of upcoming webinars here, so watch this space! The ChEMBL Team